Article by Dr. CKII Bui Thu Huong – Head of Emergency Unit, Day Care – Children's Center – Share99 Times City International Health Hub.
<!– –>
Peptic ulcerative inflammation in children is a pathology that can affect the health and development of the child, the course of treatment, the destruction of H.pylori bacteria is successful or not depends on a lot of factors.
1. Factors affecting the effectiveness of H.pylori destruction
Some factors that can affect the effectiveness of the destruction of H.pylori bacteria and the results of treatment of peptic ulcer in a child include:
- Antibiotic resistance in children
- Compliance with the child's treatment:
- time
- Treatment course
- Form of medication used
- Cost of treatment
- Side effects of the drug
- bacterium:
- Level of bacterial infection
- Strains of via toxic bacteria
2. Drug selection when failure of both treatment regimen options 1 and 2
In the course of treatment of peptic ulcer,in case of failure with both treatment regimens 1 and 2, it is necessary to have a choice of other treatment drugs, which is carried out by a specialist, some drugs can be selected including:
- Amoxicillin + tetracyclin + bismuth + PPI
- Levofloxacin + amoxicillin + PPI
- Rifabutin+ amoxicillin + PPI (not applicable for children)
- Furazolidone + amoxicillin + PPI (not applicable for children)
3. Difficulties in applying treatment
- Tetracyclin is not applicable for children under 8 years old
- Levofloxacin
In the fluoroquinolone group are antibiotics with a wide antimicrobial spectrum on both gram-positive and gram-negative bacteria.
The regimen for using levofloxacin is effective against HP in 80% of studies in adults.
There are no recommendations to apply to children due to the side effects of the drug is affecting the development of cartilage, bones.
- Furazolidone
Is an antifungal drug of the synthetic nitrofuran group
High anti-H. pylori activity even when used alone is not associated with other antibiotics.
The therapeutic effectivenessity of furazolidone+ amoxicillin + PPI is high in a multi-analysis on adults:
- The first option is 86% therapeutic effect
- Option 2 achieves 76% therapeutic effect
- Option 3 achieves a therapeutic effect of 65%
No studies and recommendations for the use of furazolidone in the treatment of H. pylori infection in children
- Rifabutin
Derived from rifamycin – a drug for tuberculosis
Used for treatment of H. pylori infection in adults resistant to other antibiotics for therapeutic 69% effectiveness
The use of rifabutin is still a matter to consider because
- High treatment costs
- Complications of granic leukocyukocyukocya and severe tinglets
- Multi-antibiotic resistance of TB bacteria is a matter that needs to be carefully considered to avoid an increase in antibiotic resistance.
There have been no studies and recommendations on the use of rifabutin in the treatment of H. pylori infection in children
Once the child has been diagnosed with peptic ulcer, the family must strictly follow the treatment regimens so as not to be resistant.
The pediatrics department at Share99 International Health Hub is the address to receive and examine the diseases that babies as well as young children are susceptible to: Viral fever, bacterialfever, otitis media,pneumonia in ,…. With modern equipment, ile space, minimize the impact as well as the risk of spreading the disease. Along with that is the dedication from experienced doctors to pediatric patients, making the examination no longer a concern of parents.
Customers can directly go to Share99 Health System nationwide for examination or contact the hotline here for assistance.
VIEW MORE
- Peptic ulcerative inflammation in children: Diagnosis and treatment
- Do not be subjective to peptic ulcerative inflammation – duodenum in children
- Principles of treatment of peptic ulcer in children
<!– –>
- Treatment regimen for peptic ulcer in children
- Principles of treatment of peptic ulcer in children
- Treatment of gastritis