Article by Ms. Ly Thi Thanh Ha – Medical Genetics Department – Share99 High-Tech Center
Genetic pathology is the result of genetic abnormalities or chromotypes, these abnormalities are transmitted from the previous generation (grandparents, parents) to the next generation (children, grandchildren).
1. Cases where genetic testing is required
Families with a history of genetic diseases, especially those with similar clinical manifestations of pathology over generations. In Vietnam, common genetic diseases are hematological diseases: Thalassemia hemolysis anemia, Hemophilia hemophilia,… myotrophic pathology: Duchenne myasthenia (DMD), Spinal Muscular Atrophy (SMA), metabolic pathology: Wilson, Citrin deficiency, …
Multiple miscarriages may be associated with genetic abnormalities or chromotypes. The first cause mainly leads to consecutive miscarriages that are hormone abnormalities, followed by genetic abnormalities or chromotypes, ultimately abnormalities associated with anatomy of the uterus or unknown causes.
The couple intends to marry a family that has historically had relatives who pose a risk of genetic diseases.
In addition, depending on the purpose of the test to be able to prescribe genetic testing in many different application cases …
2. The meaning of the types of genetic tests
Types of genetic tests have implications:
- Contribute to finding the cause of the disease, combined with appropriate treatment to support the patient.
- The degree of manifestation of a person's disease may be due to the synthesis of interactions between genetic factors (genes) and the environment, interactions between genes with each other. Finding genetic abnormalities, combined with other factors, will contribute to improving the effectiveness of treatment for patients.
- Pre-birth diagnosis: The birth of a baby with genetic abnormalities or chromosome abnormalities will be a psychological and economic burden for the family itself, and for society. Therefore, pre-birth diagnosis is extremely important to identify abnormal risks in the fetus, offer treatment options (if any) and treatment options.
- Pre-nesting embryo screening is carried out in case of necessity: Pre-nesting embryo screening has great significance, especially for rare families. The failed transfer of the embryo is caused by the fact that the embryo carries abnormalities in the number or structure of the chroma chroma. Therefore, pre-screening of embryo transfer will help to find abnormal non-carrying embryos, contributing to improving the rate of pregnancy for mothers.
- Blood determination: DNA testing plays a decisive role in determining blood ties, especially in identifying relatives of martyrs.
- Determine the risk of cancers and some chronic diseases: The difference in biological information (genes) between individuals makes each person at risk to varying degrees for cancers and chronic diseases. If each person knows his or her risk, there will be a sense of proactive prevention to preserve health, reduce the possibility of disease.
- Individualize the use of drugs and appropriate dosages for each specific subject: Previously, when it was not possible to explain why when using the drug, some people "fit" with taking this drug, people are "suitable" with taking other drugs to treat the same disease that people often say is due to "myth". To date, this can be explained entirely based on differences in the genome of each person. It is this difference that does not cause the disease but makes the difference between the treatment of each individual in terms of drugs and the dosage of use.
Recommended videos:
Vietnamese Genome: Many big surprises
SEE MORE:
- Pre-birth genetic testing chart
- Genetic screening for pregnant women over 35: What to know
- What is pre-embryo transfer genetic screening? Why should I do it?
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Hà Nội
Hanoi
Hồ Chí Minh
Ho Chi Minh City
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Phu Quoc
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Nha Trang
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Ha Long
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Hai Phong
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