Rubella is a common virus when women become pregnant. It is an infectious disease, highly contagious but preventable with a vaccine. The Rubella test is a necessity that pregnant women need to do to ensure the health of both mother and child.
1. What is Rubella disease?
Rubella is benign typhal. Infectious diseases are not critical but serious because they are capable of causing birth defects in the fetus. Rubella disease can be transmitted from mother to child through blood sugar. For pregnant women, the disease is a threat to the developing fetus.
If the pregnant woman is infected with Rubella virus during the first 3 months of pregnancy, up to 90% of cases where the mother can transmit the virus to the fetus. This virus can cause the fetus to die or suffer from congenital rubella syndrome. Therefore, the definitive diagnosis of Rubella in pregnant women especially in the first months of pregnancy is extremely important.
2. What are Rubella IgG and Rubella IgM?
The diagnosis of Rubella is usually based on the dosing immunosym test rubella IgM and IgG. Use rubella test to detect antibodies in the blood produced by the body's immune system in response to infections caused by rubella virus. IgM and IgG are two types of rubella antibodies.
After exposure to rubella virus, Rubella IgM antibodies will appear in the blood. About 7-10 days after infection, protein levels increase and peak and last for several weeks and then gradually decrease.
When the mother has rubella virus entering the body, IgG antibodies will appear. IgG antibodies will appear later than IgM but it will persist in the blood for life, helping the mother's body fight off infections caused by the Rubella virus. IgM antibodies present in the blood show that an infection may have appeared. A recent or existing rubella infection point in the past will be in point if there is the presence of IgG antibodies.
Congenital rubella syndrome can cause babies to be born with development delay, deafness … therefore, during pregnancy you should regularly test for Rubella antibodies to ensure sufficient immune response.
3. Rubella (IgG and IgM) test in pregnant women
Rubella (IgM and IgG) testing is performed for pregnant women who have never been vaccinated against Rubella and have never had rubella before pregnancy. The test should be carried out from the 7th to the 10th week of pregnancy, which is the best time to perform. It is not recommended to get tested at a pregnancy of more than 16 weeks because it is difficult to explain the results as well as if there are any problems that are difficult to solve because the pregnancy is already large.
If the IgM test is negative and IgG is positive then it proves that you have been infected with Rubella before the test for a minimum of 10 weeks, you already have a protective IgG antibody. If igg levels increase after testing 2 weeks apart, it proves that you have been infected with rubella before or have been vaccinated. If IgG levels are low, rubella may be tested for Rubella IgM and IgM after 1 week, if IgM is positive and IgG increases, patients with rubella level should be tested.
If the IgM test result is positive, IgG is negative: in this case the patient is newly infected with rubella virus, only IgM antibodies respond. You should take igm and IgG tests after 2 weeks. If the results show that IgM is still positive, IgG begins to appear, then surely the pregnant woman has been infected with rubella virus. If IgM is positive, IgG is negative then the IgM result is nons specific. Pregnant women under 12 weeks of age with a positive IgM index are 80% likely to be infected or unaccepted, and the risk of mother-to-child transmission at this stage is 80%. Children who contract the virus during this period are at very high risk of congenital rubella syndrome.
If the IgM is positive, IgG is positive: this is usually less common. It is more likely to be false positive due to a new pregnancy infected with a certain virus. Pregnant women need to be monitored and tested for IgM and IgG , after 2 to 3 times but the results of the indicators remain the same, the pregnant woman can be completely assured.
If IgM is negative and IgG is negative, it is possible that the pregnant woman has never been infected with Rubella and is at risk of contracting Rubella, this time the pregnant woman needs to be monitored regularly for treatment if she is infected with rubella. This result may also show that the patient is infected with rubella but is in the incubation period and igm and IgG antibodies have not yet been produced. Therefore, you should do the test again after about 2-3 weeks.
The risk of mother-to-child transmission of rubella in the first tri tri month of pregnancy is 80%, the risk of congenital rubella syndrome at 11-12 weeks gestation is reduced to 33%. At the time of the fetus 13-16 weeks, the rate decreases to 11-24 %, and after 16 weeks this rate is reduced to 0%. Determining the time of rubella infection for the pregnant woman is very important for the diagnosis of the condition of the fetus.
For effective prevention of rubella, it is best for women of reproduction age to get rubella vaccination before intending to become pregnant. Vaccination before pregnancy is the best way to protect the health of the mother and the fetus. Women who intend to become pregnant should go to vaccination centers, medical facilities with a stable source of vaccines.
Share99 International Health Hub currently has a full range of vaccines including Rubella vaccine, imported directly from the US, Germany of clear origin, good quality. The entire vaccine is stored in a modern cold storage system, with a gsp-standard cold storage line to ensure that the vaccine always retains the best quality. Clients will be examined by specialists, fully screened for health and physical issues, advice on vaccines and vaccination regimens, how to monitor and care after vaccination before prescribing vaccinations according to the latest recommendations of the Ministry of Health / World Health Organization to ensure the best and safest effect. most for customers.
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Nước ngoài
- What is congenital rubella syndrome?
- Diagnosis and treatment of congenital rubella
- Which cases are susceptible to newborn infections?