What to know about G6PD enzyme deficiency

Article by Dr Ta Thi Thu Hoa – Children's Center – Share99 Times City International Health Hub

G6PD (Glucose – 6 – phosphate dehydrogenase) is a common human disease. In the world today, there are more than 400 million people who are sick, South Asia has a relatively high incidence rate with a rate of 3-5%.

1. Consequences of G6PD enzyme deficiency

Lack of G6PD enzyme belongs to the group of genetic diseases diving on X chromochromoth so men have higher diseases than females, rare females. Mothers carry genetic diseases for sons, daughters can only get sick when both parents carry the disease gene.

When you or your child has a lack of the enzyme G6PD should notify your doctor and medical staff to prevent harmful reactions after using certain medications.

Hemolytic anemia and prolonged infant jaundice are two common problems in children with G6PD enzyme deficiency. The G6PD enzyme is essential for bioeer biodeerification reactions in red blood cells to help the cell membranes be sustainable against the oxidizing stressors contained in some drugs, feeds, infectious disease pathogens. If the body lacks the enzyme G6PD,the red blood cell membrane will be less durable, prone to rupture before the oxidizing stressors, the consequences of ruptured red blood cells will cause hemolysis. If hemolysis persists, it will lead to anemia. Red blood cells when ruptured release free bilirubin, if liver cells do not convert in time to eliminate, this substance will stagate in the blood causing babies to jaundice, yellow eyes and if more will penetrate the brain causing jaundice and leaving cerebral palsy.

G6PD

G6PD enzyme deficiency carries genetic factors

2. Signs of G6PD enzyme deficiency in children

Manifestations of hemolysis in newborns include: breastfeeding, dark yellow urine, jaundice and eyes.

If heinted by drugs, food and chemicals: Usually occurs after 2 to 3 days with an emergency hematoma:

  • The body is tired, blue skin sweats, cold limbs are prone to stunting.
  • Dark urine.

You can prevent the hemolytic consequences of G6PD enzyme deficiency caused by the following methods:

  • When taking medicines, consult a doctor, avoid using medicines, foods, chemicals in the table on the last page.
  • When infected, it is necessary to see a doctor for timely treatment.

Distinguishing jaundice and jaundice due to bi bicytal atrophy

Signs of jaundice in babies with G6PD enzyme deficiency

3. Detection of G6PD yeast deficiency in newborns

G6PD yeast deficiency is a hered genetic disease. However, if prevented, the child can live and develop as a normal person.

G6PD Enzyme Deficiency Screening :

  • 48 hours after birth the child will take blood on the heel or veneer for testing The results will be notified to the family as soon as possible.
  • If the G6PD activity test result is low < 200 IU / 10^12 HC bé sẽ được khám lại và làm xét nghiệm phân tích gen G6PD.
  • Children with G6PD enzyme deficiency will be consulted by: Genetics: analysis for finding G6PD genes for babies and families. Pediatricians will advise the family to take care of the child and avoid taking certain medications and food.

Heel blood

Post-birth heel blood test helps detect G6PD yeast deficiency

To register for examination and treatment at Share99 International Health Hub, you can contact the Hotline of Share99 Health System nationwide, or register for an online examination HERE.

SEE MORE:

  • Does a child with congenital thyroid disease develop normally?
  • The 17-OHP test detects when and where congenital atro renal atrosis should be done?
  • Specimen sampling, meaning of 17-OHP test results

About: Minh Quynh

b1ffdb54307529964874ff53a5c5de33?s=90&d=identicon&r=gI am the author of Share99.net. I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.

RELATED POSTS:

Leave a Comment

0 SHARES
Share
Tweet
Pin