Learn about anti-androgens syndrome

The article was consulted professionally by Specialist I Pham Thi Yen – Obstetrician and Gynecologist – Share99 Hai Phong International Health Hub.

The patient's anti-androgens syndrome is female in appearance but has a male genotype. Patients have mammary glands and external genitals like females but are asym neurotic when they reach puberty. This anti-androgens syndrome is usually detected when there is a problem of infertility or accidental examination.

1. Anti-androgen syndrome

Androgen resistance syndrome is a mutation of the gene located on the near segment of the long branch NST X, and heredity according to the diving gene characteristics. This results in the fact that the cell does not respond in part or to a complete response of the cell to the androgens that hinder the masculinization of the fetal genitalia.

Most often, female fetuses often suffer from complete anti-androgens syndrome, while somewhat anti-androgens syndrome may appear in male or female females and be diagnosed at birth, based on abnormal genitals, but other forms may not be diagnosed until puberty.

People with anti-androgens syndrome cannot have children, but still live normally healthy lives.

X and Y chroma

X and Y chroma

2. cause

The cause of anti-androgens syndrome may be genetic errors from the mother transmitted to the child. Although male despite being heredity, the body does not respond to testosterone and the problem of developing male genitalia is not normal, the penis develops or does not form. The genitals of the child can be female or between female and male, but without ovaries and uterus, have a part or not testicles completely.

3. Manifestations of the disease

At birth, the child has the same anti-androgens syndrome as a normal baby, with no signs of abnormalities. During puberty there is a tendency to start softer than other girls. The mammary glands develop, the pelvic structure and fat distribution on the body still occur like other girls.

However, patients have very little, even no pubic hair, or male-style distribution. The skin of the patient's face is usually more beautiful than his peers, without acne because the oily glands do not respond to the stimulation of androgens.

The process of puberty is not much different from other girls, except that the person does not have menstruation. Physical examination, sparse pubic hair can be seen or no pubic hair. The external genitals are female with a short vagina, and the cervical uterus is not visible.

Therefore, the vagina usually ends up being a same bag, with absolutely no communication with the inside. When ultrasound does not see the uterus and two ovaries. The person is completely incapable of reproduction. In addition, it is possible to touch the bulge in the inguinal area due to the team's testicles. Most are not palpable because the testicles are usually inside the abdomen.

To diagnose anti-androgens syndrome it is only necessary to perform NST schemes.

Girl with gynecologic inflammation

Children with anti-androgens syndrome are like a normal baby

4. treat

Due to the syndrome of anti-androgens is accompanied by complicationsof infertility , and sexual insular consistency is easy to make the patient's sexual girlfriend feel afraid. Therefore, people with the disease are often vulnerable, so deciding how to inform the patient must put the interests of the patient first.

The majority of patients will feel bewildered and distressed, dissatisfied. Therefore, it is necessary to have a strategy to advise and provide mental support to patients immediately afterwards with the system approaches that need to be meticulously prepared in advance.

In addition, it is necessary to intervene in a number of other issues such as:

  • Vaginal extensiveness: if the women have difficulty having sex due to a narrow vagina. However, the vagina can expand itself gradually due to its ability to dilate itself after a period of sexual contact. Vaginal reconstruction with surgical intervention can be done for adults, but can also cause some complications.
  • Removal of the testicles: is a matter of debate. Until the moment after puberty the benefit of the testicles is that there is no need for the use of endeer endoscopy. This occurs because the testosterone that the testicles produce is converted into estrogen. Some suggest that the testicles in the abdomen can progress to a benign or malignant tumor.
  • Estrogen replacement: if the testicles are removed, it is necessary to use estrogen instead to support the process of puberty, which helps the growth of bones and is complete during m maturity.

Establishment of gynecology clinics

Patients should go to a reputable facility for timely examination and treatment

Anti-androgens syndrome is a rare syndrome and has a family nature. The diagnosis of this syndrome is not difficult, however difficult to detect. In terms of treatment, until now, medicine has been studying these diseases related to genetic abnormalities in general, and anti-androgen syndrome in particular.

Dr Pham Thi Yen has 11 years of experience in examination and treatment in the field of Obstetrics and Gynecology. Doctors with strengths and insights in:

  • Examination and consultation of common pregnancies, pathology pregnancies, high-risk pregnancies
  • Examination and treatment of gynecologic diseases: cervical inflammation, cervical glands
  • Laparoscopic surgery of gynecological diseases : extra-uterine pregnancy, uterine tumor , ovarian tumor
  • Surgery for breast tumors, vaginal, cervical tumors
  • Obstetric surgery : pregnancy surgery, examination
  • Treatment of female endormonal disorders of all ages: puberty, reproduction age; pre-menopause.

For direct advice, please click hotline number or register online HERE. In addition, you can register for remote consultation HERE

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About: John Smith

b1ffdb54307529964874ff53a5c5de33?s=90&r=gI am the author of Share99.net. I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.

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