Hematoma is a slow-progressing form of blood cancer. The disease increases the viscosity of the blood, the formation of blood clots and the appearance of complications if not treated in time will affect life.
1. What is polyethular disease?
Polycythemia vera (PV) is a rare blood cancer. The disease occurs when the bone marrow produces too much blood cells, in which red blood cells are most produced.
Polycythemia is a consequence of the excessive production of blood cells (especially red blood cells) that increase the viscosity of the blood causing the blood to flow slowly, creating favorable conditions for the formation of blood clots.
Slow bleeding reduces the body's ability to supply oxygen. Blood clots in the vessels increase the risk of strokes, vascular accidents, fibroid rupture of arteries, blockage of arteries, etc. even fatal to the sick.
Prolonged disease also increases the risk of other conditions such as leukemia and some other types of cancer. Therefore, the patient needs to be treated promptly, preventing the risk of complications.
The original polyethular disease cannot be completely cured but can be treated in a timely manner to control the condition. Patients should follow treatment and re-examine on time to prevent blood clots from becoming more severe.
2. Symptoms of the disease
Symptoms of primitive polyeths include:
- Difficulty breathing while lying down
- Bleeding or bruising.
- Full left abdomen above (due to enlarged spleen)
- Headache, difficulty focusing
- Itching, especially after a warm bath
- Shortness of breath
- Inflammation of the veins
- Blue skin
- Vision problems (blurred vision or double vision)
- Unexpected weight loss
- Debilitating body
- Sweating a lot
As the disease progresses more severely, serious symptoms may appear such as:
- High bleeding from small wounds
- Osteoarthritis pain
- Bleeding in the gums
- Burning in the hands or feet
3. Complications of the disease
Complications of primitive polyeth esthose cells include:
- Enlarged spleen: The increased size of the spleen is due to having to work more to filter the increased amount of blood cells.
- Causes a number of diseases: Peptic ulcer, inflammation of the joints of the bones (gout).
- Bone marrow disease: Osteomyeloid fibrosis, abnormally developed bone marrow syndrome, acute leukemia, etc.
4. Risk factors for disease
Factors that increase the risk of developing primitive polyethular disease include:
- People with a history of blood clots
- People over 60 years old
- People with a history of certain diseases such as hypertension, diabetes, high cholesterol.
- People with bad habits such as smoking, drinking, using drugs.
- Women in pregnancy
5. Diagnosis of primitive persimm
5.1 Main standards
The main diagnostic standard of primary red blood cells includes:
Blood formula test:
- Hb > 185 G/L (male), > 165 G/L (female)
- Hb > 170 G/L in men, > 150 G/L in females (if combined with Hb increases sustainably by ≥ 20 G/L compared to normal without iron treatment)
- Increase the volume of global red blood cells > 25% of normal values
Test to test for mutations of JAK2V617F gene: JAK2V617F mutation
The standard of secondary diagnosis of primitive red blood cells includes:
- Marrow: Growth of 3 lines of pulp cells
- Serum erythropoietin test: Serum erythropoietin levels decrease.
- Bone marrow biopsy: EEC (endogenous erythroid colony) cluster appears when cultured without erythroids
Primary polyeth red blood cells are determined when there are both primary and 1 sub-standard or the first primary standard and 2 sub-standards.
6. Treatment of hem of hem of red blood cells
General principles of treatment of hemage polyethage include:
- Active treatment of cardiovascular risks.
- Hematocrit maintenance bleeding < 0,45.
- Aspirin dose 75 – 100 mg daily, unless contrained.
- Anti-cellular drugs are in dinhed based on different individual characteristics.
A number of specific treatments are applied, including:
- For patients under 40 years of age, asymptomatous: Perform a mere blood draw method to maintain hematocrit < 0,45.
- For patients with a history of embolitis or hemorrhage, elderly: Treatment of cell reduction with hydroxyurea (initial dose 10-20 mg/kg/day, maintenance dose depends on each individual, mainly based on the test of total peripheral blood cell analysis).
- For pregnant women, patients with hydroxyurea intolerance: Treatment with Interferon-alpha, the initial dose is 3 MU/day (intramuscularly or subcutaneously) until hematocrit is reached < 0,45, liều duy trì được lấy từ liều thuốc thấp nhất mà vẫn kiểm soát được lượng hematocrit.
- For elderly patients (over 65 years old): Radioactive phosphorus treatment can be applied (not applicable to young patients to avoid the risk of developing radiothal lashings).
In addition, patients are also treated for support and prevention of embolism complications caused by low-dose aspirin (75mg/day) and iron-assisted treatment for patients with repeated iron deficiency (decreased serum iron and ferritin levels).
7. Measures to prevent the disease from progressing
Lifestyle and home remedies can help slow the progress of the development of the main polyethular disease, which includes:
- Exercise: Walking, slow running, etc. helps improve blood circulation, avoid blood clots.
- Do not smoke to reduce the risk of myocardial infarction, blood clot stroke.
- Take care of your skin with a cool bath or shower, using moisturizer to keep your skin healthy.
- Maintain a stable body temperature: Avoid exposure to overheated or too cold temperatures that limit blood circulation such as dressing appropriately for the weather, avoiding exposure to hot or cold items, eating a lot of hot or cold items, etc.
- Take care of the wounds on the body carefully.
Customers wishing to see and treat diseases at Share99 International Health Hub, can directly go to Share99 Health System nationwide for examination or contact the hotline here for assistance.
- Is polyething disease in babies dangerous?
- What is the number of red blood cells in the body?
- How long do red blood cells live?
- Does polyething disease have a cure and treatment?
- Complications of autodive hematoma
- Basics of blood