Measles vaccination with rubella in immuno-impaired humans

The article is consulted professionally by BS. Nguyen Hai Ha – Head of Vaccine Unit – Pediatric Outpatient Department – Pediatrics Center – Share99 Times City International Health Hub.

Immuno-deterioration can be caused by a variety of conditions, including congenital immuno immunopathy, human acquired immuno-depletion virus (HIV) infections, other conditions such as leukemia, lymphoma. Immuno-impaired patients are recommended to be vaccinated with MMR II for protection from measles, mums, and rubella.

1. What is the MMR II vaccine?

MMR II is a live vaccine, detoxifying against 3 diseases: measles, mums, rubella. It is a larva frozen product of a weaker stream of measles virus, derived from the weakened strain of Edmonston of Enders and bred in cell culture.

2. Pharmacology of the MMR II vaccine

Measles, mums, rubella are three common diseases in children, caused by the measles virus, mums, rubella. They can be associated with serious complications or lead to death. For example, pneumonia and encephalitis are caused by measles. The quadrum is associated with aseptic, deaf meningitis. Rubella during pregnancy can cause congenital rubella syndrome in babies of infected mothers or cause fetal malformations such as deafness, brain calcification, causing miscarriage, premature calving.

Clinical studies have demonstrated that MMR II has high immunity and good tolerance. One vaccination in which antibodies inhibit hemagglutination (HI) in 95%, the quaim is antibody neutral at 96% and rubella HI antibody at 99%.

3. Recommended vaccination schedule

The MMR II vaccine is intrained for simultaneous injections against measles, mums and rubella in children and adults 12 months and older. The Advisory Committee on Immunization Practice (ACIP) recommends using the first dose of MMR II at 12 to 15 months of age and using a second dose of MMR II at 4 to 6 years of age (usually 4 years away from the first dose).

Tuberculosis vaccination at Share99

Measles, Mumm and Rubella vaccines can be given to children 12 months and older

4. Groups of subjects should be vaccinated with MMR II

4.1. Children from 9 to 12 months old

The smaller the child, the lower the ability to convert serum. Children 9 months old should be vaccinated against measles. If a single measles vaccine is not available, it can be given instead of a measles-mummun (MMR II), after which the child will receive a second dose of MMR II between 15 months of age (at least 6 months from the dose of 1) and repeat the MMR II dose 3 vaccine after a 2-year dose (may be earlier if there is an epidemic , about 4-6 years old).

4.2. Women of child and adult age

The MMR II vaccine is insularly given to adolescents, non-pregnant adults. After vaccination it is necessary to contraception for at least 1 month, at best 3 months. Vaccination helps protect the body of people vaccinated from measles- mums – rubella. Also resistant to measles, rubella infection in pregnancy, thereby preventing infections and birth defects of the fetus due to measles or rubella.

4.3. Other populations

Children 12 months and older who have not been vaccinated in advance should be vaccinated with MMR II to reduce the risk of infection. People planning to travel, if not immune, can get measles, mums or rubella during travel. Therefore, before traveling internationally should be vaccinated.

4.4. Group of patients with immunod depletion due to HIV virus infection

For children living with HIV, the MMR II vaccine is still recommended for children at least 12 months of age or older if there is no severe immunodurged, AIDS phase. Because not vaccinated, measles, rubella can affect and cause serious complications for these patients.

Assessment and testing of HIV infection in children is not necessary before making a decision on immunization of live virus vaccination. If the child is at risk of exposure to measles, monogen-monogen measles should be vaccinated at the age of 6-11 months at a second dose (MMR) older than 12 months (at least 6 months from the single measles vaccine).

Patients with severe immuno immunosmmunity and HIV-infected patients with symptoms exposed to measles should be given immunoglobulins (IG),without prior vaccination concerns. The recommended dose of IG for the treatment of measles prevention of immuno-impaired people is 0.5 ml/kg of body weight (maximum dose, 15 ml). The immunity of the measles vaccine will decrease if the vaccine is given less than 6 months after IG.

5. Contrained for measles, mums and Rubella vaccines

The following individuals should consider not vaccinating or delaying MMR II vaccination:

  • People who are hypersensitive to any component of the vaccine, including gelatin.
  • Do not inject MMR II to pregnant women, it is recommended to avoid pregnancy for at least 1 month and at best 3 months after vaccination.
  • Patients are being treated for immunosuppressive drugs, high-dose corticoids equivalent to Prednisolon > 2mg/kg/day. This contrainttraint applies not to patients who are taking corticosteroids as an alternative therapy, for example, to Addison's disease.
  • People with leukemia, lymphoma of any type, or other malignant tumors that affect the bone marrow or lymphatic system. Patients with tinglet reduction
  • People with tuberculosis are progressing without treatment.
  • Subjects with fever, respiratory diseases or ongoing infections.

Currently, Share99 International Health Hub provides MSD (USA) MMR II / Diluent Inj 0.5ml vaccination services that prevent 3 diseases: Measles – Mumps – Rubella for children 12 months and older and adults.

velvet-loai-vaccination-ban-co-tiem-hoac-hoac-painting-during-pregnancy

Infants should receive a second dose of the Measles, Mumi and Rubella vaccine between 12 and 15 months of age

The advantages of vaccination at Share99 International Health Hub include:

  • Before vaccination, all clients are screened for pre-vaccination with pediatricians to help them ensure the best health when vaccinated. Doctors will advise on age-appropriate vaccines according to the latest recommendations of the Ministry of Health and the World Health Organization as well as how to monitor the post-vaccination response.
  • A team of experienced, professional pediatric doctors and nurses, understanding the child's psychology helps the family feel secure during the vaccination process.
  • 100% of vaccination subjects are monitored and re-evaluated before leaving.
  • The post-vaccination monitoring room is fully equipped with emergency facilities; doctors and nurses are trained in emergency treatment of counter-toilets to ensure timely and correct treatment when incidents occur. In addition, Share99 Health Hub system always has an emergency ekip ready to coordinate with the vaccination room to handle cases of anaphylactic shock, respiratory failure – stop existing to ensure the safest vaccination for children.
  • The vaccination room is airy, has a play area, helps children feel comfortable like walking around and have a good mentality before and after vaccination.
  • Vaccines are imported and preserved in modern cold storage systems, with a GSP-standard Cold chain, with a refrigerator containing vaccines in each injectable room as a dedicated refrigerator can still ensure a temperature of +2 to +8 degrees Celsius when power is lost within 24 hours , to keep the vaccine in the best condition to ensure quality.
  • Currently, Share99 is building software that can check the child's vaccination history or schedule reminders so that parents do not forget their child's vaccination schedule via computer or phone conveniently.
  • Vaccination information will be synchronized with the national immunization information system.

Dr. Nguyen Hai Ha worked for many years at the Department of Pediatrics – Infants of Thanh Nhan Health Hub – Hanoi and the Department of Infants – Share99 Times City International Health Hub before taking up the position of Head of Vaccine Unit of Pediatrics Department of Share99 Times City International Health Hub today.

For direct advice, please click hotline number or register online HERE. In addition, you can register for remote consultation HERE

Source reference article: CDC

SEE MORE:

  • How many shots is enough for measles vaccine – mums – rubella?
  • Vaccines to be given to women aged 13-18
  • What is congenital rubella syndrome?

About: John Smith

b1ffdb54307529964874ff53a5c5de33?s=90&r=gI am the author of Share99.net. I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.

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