Endometrial growth and cancer risk

Endometrial probing is an increase in the number and density of endometrial gland cells caused by excessive estrogen stimulation without changes in progesterone according to the menstrual cycle. It is the excessive growth of endometrial cells that the cells that make up this lining will increasingly crowd each other and become abnormal, and can lead to cancer in some cases.

1. What is endometrial growth?

Endometrial growth is an endometrial condition or the lining of the uterus becomes too thick because of excess cell growth. Although this is not cancer, this disease can lead to cancer of the uterus in some cases.

Endometrial is capable of changing throughout a menstrual cycle in response to hormones. At the beginning of the cycle, the estrogen hormone produced by the ovaries will help the mucous layer to grow and thicken to prepare the uterus for pregnancy. Next, in the middle of the cycle, the eggs are released from the ovaries (ovulation). After ovulation, other amounts of hormones called progesterone begin to develop. Progesterone prepares for endometrial acceptance and nourishment of fertilized eggs. Without pregnancy, both the hormones estrogen and progesterone will gradually decrease. When progesterone begins to decrease, it produces menstruation or peeling of the mucous layer. When the mucous layer is completely exfoliative, a new menstrual cycle begins.

Endometrial pro proogenosis usually occurs due to excessive estrogen but lack of progesterone. If ovulation does not occur, progesterone is not produced and the mucous layer will not peel off. Endometrial may continue to increase in response to estrogen. Cells that form the mucous layer can accumulate together and may become abnormal. If not treated properly and promptly, the disease can progress to cancer.

In endometrial growth is divided into 4 types:

  • Simple growth: There is an increase in the number of glands, but the gland structure is normal.
  • Complex growth: There is also an increase in the number of still glands but structural changes.
  • Typical eugenics: Is the non-presence of atypical cells.
  • Atypical growth: As a birther there will be the presence of atypical cells.

The reasons for this division are based on the natural developments of the disease:

  • Typical 2% simple births progress to endometrial cancer.
  • 8% of typical complex births progress to endometrial cancer.
  • 23% of atypical births progress to endometrial cancer.

2. What are the most common diseases?

obesity

Common diseases in obese women

Endometrial retriosis can be seen in many women, but the most commonly encountered are the following groups of subjects:

Around puberty

Girls around puberty, due to the un perfection of the genital apparatus, ovulation occurs irregularly. Therefore, the appearance of menstrual rings without ovulation, without ovulation in these subjects prevents the lua body from forming, causing abnormal hormone cycles from which to entail the growth of the endoratometrial.

Use of drugs of a female hormone nature

The use of drugs of a hormone nature in the pre-meniciveperiod , menopause to reduce unpleasant symptoms in the body is something that is applied by some women. But due to the intervention by taking this hormone supplement makes it impossible for hormone levels in the body to change in an inherent cycle but always in a high state.

High concentrations of female sex hormones in the body constantly cause the endo will also increase continuously. This prolonged condition causes endometrial growth to progress into pathology.

Irregular menstrual cycle

Irregular menstrual cycles are also a factor that increases the risk of endometrial growth. Irregularities in the menstrual cycle, too long or too short cycles also cause the endo will give rise abnormally and can progress into pathology.

obesity

Obesity is also known as one of the common causes of endometrial hyperglyctivitis. This is because when obese, the body is capable of producing a much higher than normal amount of the hormone Estrogen. The normal excess production of the hormone estrogen is the driving cause for endometrial growth. Therefore capable of causing endometrial fisses.

3. Causes of endometrial growth

Some evidence suggests that endometrial pros pros proogenym is a consequence of the excessive presence of the hormone estrogen without progesterone. If ovulation does not occur, progesterone will not be formed and the lining of the uterus will not peel off. The endo will continue to grow, responding to the amount of estrogen in the body. The cells that make up the lining will increasingly crowd each other and become abnormal. This condition is called birth, which can lead to cancer in some women. Since this hormone imbalance is also associated with bowel cancer, twin births are sometimes considered pre-cancerous conditions. Women who are less exposed to the hormone progesterone, near menopause (when erratic ovulation) or post-menched women (when ovulation has stopped), some adolescents who have just passed puberty and have not yet formed a regular ovulation cycle are at higher risk for this disease.

In addition, estrogen replacement therapy does not add progestins and the breast cancer drug tamoxifen may also be the cause of this condition.

HRT

Estrogen replacement therapy without progestins may also be the cause of endometrial pros proogenymosis

4. Symptoms of endometrial growth

Endometrial growth has many different manifestations, but can sometimes be ignored if not really noticed. Some common symptoms of endometrial growth such as:

Abnormal hemoma

Abnormal neuron blood is one of the most typical symptoms of endometrial growth. The increase in growth causes the endometrial layer to thicken, followed by an increase in blood vessels to nourish the endoratometrial layer. Therefore, when it comes to menstruation, along with the peeling of the endometrial layer is the rupture of a lot of nourishing blood vessels that cause more menstruation than usual.

Abnormal bleeding

Abnormal bleeding is also common in cases of endometrial hypertension. When abnormal endometrial layer is born, if neo neolytic blood vessels are insufficient to supply blood to this endotriosis layer causes them to suffer from hypoxia and necrosis. Necrosis areas of the endoratinal layer cause the remaining blood vessels to break and cause abnormal blood clots even though it is not yet menstruation.

Bleeding after menopause

This is an important abnormal sign that women who have entered the menopause need to remember, especially those women who use drugs of a female hormone nature to alleviate the symptoms of this period. Uterine bleeding at this stage in addition can be a signal of endometrial growth, which can also be a signal of a tumor, or a malignant pathology in the uterus,…

Ultrasonic Signs

Signs on ultrasound are also important signs that contribute to the diagnosis of endometrial hypercoctivitis. Patients may inadvertently detect endometrial hypercoctivitis when going for an ultrasound of another disease or go directly to the uterus ultrasound when there is bleeding, abnormal menstruation.

Symptoms manifested by endometrial hyperenctivitis when ultrasound will manifest it by abnormal thickening of the endotriosis layer on the display screen. When the endometrial layer of women at child's age is more than 12mm thick, and greater than 5mm at menopause without the use of endometrial replacement drugs, endometrial thickening is suspected.

menses

Abnormal neuron blood is one of the most typical symptoms of endometrial growth

5. Complications of endometrial growth

Complications of endometrial growth are generally not so rampant with severe complications that occur instantly. When there is endometrial growth, patients mainly experience the following complications:

Annoying

Endometrial birth causes the patient to have a lot of menstruation, abnormalities, irregular menstrual cycles that greatly affect the patient's life.

anemia

In addition to affecting the patient's psychology, menstruation, prolonged periods can also cause complications such as anemia caused by blood loss. Anemia in patients with endometrial hypertension depends on the patient's more or less bleeding. When the patient has a rush, it causes an emergency anemia, when the patient has prolonged bleeding, it is easy to cause chronic anemia.

Therefore, patients with endometrial growth should pay attention to the addition of substances beneficial to the hematoma such as iron, protein, …

Progressing to cancer

Progressing to cancer is the most severe complications of endometrial growth. Although the likelihood of progressing to cancer of the disease is quite slow, without proper and timely treatment, endometrial growth will most likely escape from the rules of regulation, inhibition of the body and cause cancer.

The progress to cancer of endometrial growth is often not the same, but varies with the type of birth. For patients with simple birth growth typically the rate of progress to cancer is 2%. Typical complex birthing patients have a rate of 8%. Atypical complex patients have a cancer conversion rate of up to 23%.

6. treat

In order to treat endometrial mentitis, it is necessary to clearly determine what type of pathology this is, as well as the cause of the disease, to be able to give the appropriate treatment direction. For typical progeny without atypical deformity cells, the risk of progressing to cancer is only 1-3%, so the treatment direction will be medical treatment with progestins, which can be taken in the form of oral, injectable …. Ultrasound will be a follow-up measure based on the measurement of endometrial thickness. Depending on clinical improvement (manifested by haemolysis), an endoscopic intervention or a bio-examination may be required after 3 months.

Particularly for people with pre-menicausal age and menopause with complex, typical, a uterus removal may be considered. With an atypical form of birth that has an 8-30% risk of turning into cancer, the predisposition to treatment will also be a uterus removal. But if the woman is young, or not enough children, she will try to treat her with medication, if the condition does not improve to have a uterus removed.

7. prevent

Overweight

If overweight, it is recommended to lose weight. Risk of endometrial cancer increases with obesity levels

The following steps can be followed to reduce the risk of endometrial growth:

  • If estrogen is used after menopause, progestin or progesterone should be used.
  • If the menstrual cycle is uneven, the doctor will recommend taking additional contraceptive pills. They contain estrogen along with progestin, other forms of progestin can also be used.
  • If overweight, it is recommended to lose weight. The risk of endometrial cancer increases with the level of obesity.

Thereby, endometrial growth is a rather dangerous disease in women when it can turn malignant. But with these symptoms, using ultrasound can still detect the disease early and treat the disease in a timely manner before the disease brings severe symptoms.

Endometrial reproduction is a complex pathology that affects the health of the woman as well as their fertility. Therefore, women need to monitor the menstrual cycle regularly, if the menstrual cycle has any disorders that require early obstetric and gynecological examination for a positive treatment direction, avoiding the level of serious disease new treatment will be difficult and require more long-term treatment.

In order to help customers detect and treat gynecologic diseases early, Share99 International Health Hub has a basic gynecologicexamination and screening package, helping customers detect inflammatory diseases early, making treatment easy and inexpensive. Screening for early detection of gynecologic cancer(Cervical cancer) even if there are no symptoms.

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  • Abnormal bleeding of the vaginal area
  • Menstrual problems: abnormally long cycles, irregular menstruation
  • Abnormal vaginal translation (bad smell, unusual color)
  • Pain, itching of the closed area
  • Female customers have a few risk factors such as bad personal hygiene, unsafe sex,abortion, ,…
  • Female customers have other symptoms such as abnormal vaginal discharge, itching, pain in the closed area, abnormal vaginal bleeding.

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For direct advice, please click hotline number or register online HERE. In addition, you can register for remote consultation HERE

SEE MORE:

  • Uterus biosy: What to know
  • Signs of female hormones
  • The secret life of hormones in the body

About: John Smith

b1ffdb54307529964874ff53a5c5de33?s=90&r=gI am the author of Share99.net. I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.

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