Respiratory failure caused by diaphragm in premature babies

Acute respiratory failure in babies is one of the leading causes of infant mortality. Acute respiratory failure usually occurs in relation to diseases of the lungs and respiratory system.

1. What is respiratory failure caused by diaphragm in premature babies?

Respiratory failure caused by diaphragm is a common condition in premature babies under 32 weeks of gestation due to surfactant deficiency (rare in children over 35 weeks of age). Statistical research shows that in the inevitable membrane disease can be seen in all infants at a rate of 1%, in premature babies it is 10%, up to 30% of sick babies are under the age of 30 weeks.

Surfactant is an extant alveolar surfactant, which is introduced into the lungs of babies through the intestation to help fight alveolar collapse caused by respiratory distress conditions. Therefore, a deficiency of surfactant in the body or inactivation surfactant will cause the alveoli to collapse, reducing the elasticity of the lungs, thereby causing respiratory failure.

The production of surfactant in the body is intimately related to the enzymatic system in the body. However, in premature babies, this genome is incomplete, the catalystized enzyme system increases surfactant synthesis is also incomplete. This enzyme system works only well when the pregnancy at the stage of 34-35 weeks becomes. Therefore, premature babies are always at higher risk of diaphragm than others.

Diaphragm consists of two main types:

  • Primary in-domestic membrane disease: Common in premature babies.
  • Second membrane disease: Seen in children who are nearly full months and full months, in cases where the mother has diabetes mellitus,the child has severe pneumonia, or the child has pneumonia caused by inhalation of stools, asphyxiation during childbirth, pulmonary hemorrhage …

Causes of acute respiratory distress caused by diaphragm in young children:

  • The most common cause of respiratory failure is due to surfactant deficiency in the body.
  • Due to the respiratory system of an adult child.

This leads to one consequence:

  • Collapsed lungs, collapsed pulmonary alveoli
  • Decreased blood oxidation
  • Blood acidosis
  • Pulmonary vascular spasms
  • Acute and chronic pulmonary mesthotulmonary lesions

Risk factors for acute respiratory distress caused by membrane disease:

  • Premature babies
  • Mum has diabetes
  • Asphyxiated
  • Cases of multiple pregnancy or placenta peeling young

2. Clinical manifestations of upper membrane respiratory failure

Respiratory failure in children

When a child has trouble breathing is one of the clinical manifestations of respiratory failure in
  • Children have difficulty breathing, often breathe quickly, their noses are bulging, moaning at exhalation
  • There is contraction of intersecting muscles, concave sternum
  • Purple, pale skin. Violet can occur at the head of the genus, severe in the center including the lip mucosa and oral mucosa
  • Hearing the lungs see a decrease in alveolar fences, which can suffer peripheral edema due to water accumulation

Symptoms of acute respiratory distress in inner membrane disease may appear within minutes or hours of calving, complications of respiratory failure in premature babies usually progress severely within 48 hours. The disease peaks on the 2nd and 3rd day after birth, which is the most fatal period in the child.

Membrane disease is mainly diagnosed based on clinical results that are usually based on chest X-ray imaging to assess the collapse of the lungs.

3. Surfactant pump therapy for diaphragm disease

Surfactant pumps for newborn respiratory failure: Things to keep in mind

Surfactant pumps treat respiratory failure caused by diaphragm disease

To treat acute respiratory failure caused by diaphragm disease, it should be noted that a combination of various support methods including oxygen breathing, control of monitoring of survival indicators, limiting the impact on the child and importantly overcoming the causes of all these conditions.

As said above, surfactant is an important substance that activates the alveolar surface to combat the collapse of the alveoli. Therefore, they are important in the treatment of membrane diseases in the clearing.

Surfactant therapy is in dinhation in case of moderate and severe respiratory failure:

  • The child has acute respiratory failure due to inflammation of the upper membrane.
  • Children with stool inhalation pneumonia – Membrane disease in cesarean section without labor should be considered for surfactant therapy when there is a FiO2 > 50%, airway average pressure > 10 – 20cmH2O or oxygen index over 15 within 6 hours.
  • X-rays show membrane disease in level II.

Note that surfactant therapy should be considered with caution in the following cases:

  • Infants with membrane disease in premature birth at less than 26 weeks of age, or babies born with non-standard weight (less than 1000g light).
  • The child shows signs of severe pulmonary hemorrhage and the disease is tending to progress.
  • Children with asphyxiation, severe brain hypoxia or brain haemorrhageo.
  • Children with severe birth defects.
  • The family refused treatment with surfactant therapy.

Surfactant pumping techniques will be difficult to implement if the general care standard is not of high quality. Share99 has met the strict standard conditions for applying Surfactant therapy in the treatment of respiratory failure caused by internal membrane disease in premature babies, including a full range of supporting facilities and a team of doctors proficient in the techniques: Intt management, use of ventilators, handling of respiratory emergency situations , dealing with cases of pediatric patients with pleural gas overflow.

For more detailed information and further advice on Surfactant pumping techniques for newborn respiratory failure at Share99.

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About: Minh Quynh

b1ffdb54307529964874ff53a5c5de33?s=90&d=identicon&r=gI am the author of I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.


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