Dosing proteins in the urine: When to do it?

The article was conducted by Master, Dr. Nguyen Thi Mui – Laboratory Department – Share99 Ha Long International Health Hub.

Protein index in urine helps to determine the amount of protein in the body. When proteins appear in large quantities in normal urine, this can be one of the important indicators of urinary kidney pathology.

This test is to detect and/or quand the protein in the urine that escapes from the body through urine. Normally, the amount of total protein in the urine < 150 mg/ngày (24 giờ), Albumin nước tiểu < 30 mg/ngày. When the urine total analysis test usually gives a negative proteinuria result.

When proteins are found in the urine, there are 2 possibilities:

• It is possible that protein increases temporarily in cases where people are infected, stressed, pregnant, dieted, have a cold or physical exertion. In these cases, the amount of protein in the urine is small (usually traceable).
• There are persistent proteins in the urine, suggesting there may be damage to the kidneys or some other pathology that requires further examination to find the cause.

There are several types of tests that determine the quantities of proteins in the urine and use them as follows:

• Semi-dosing protein test using the "dipstick" test bar, try urine in the morning or try urine at any time. This is a test that has usually been included in the urine total analysis test. May be prescribed by your doctor every time you have a medical examination, medical examination or a test before there is a protein in your urine. Test results are answered in the form of "Stain", "1+", "2+", "3+", "4+"
• 24-hour urine protein dosing: Made of urine samples collected over the course of 24 hours, the test result is the amount of protein released into the urine in 24 hours.

This test is in place in case the test bar urine test detects that there are many proteins (≥ 1+) or there are persistent proteins in the urine, monitoring the progress or results of treatment of kidney damage, other pathology that drains proteins into the urine.

It should be noted that this test results are only really true if the entire amount of urine in 24 hours is fully and properly collected.

• 24-hour urine albumin dosing: Made with the above 24-hour urine sample, the test result is the amount of Albumin released into the urine in 24 hours. In the case of a test-bar urine test for protein, or for early detection of kidney damage in cases of chronic disease with damage to the target body of the kidney (e.g., diabetes mellitus, Hypertension, Lupus, goute,…). As well as the proteinuria dosing test, with this test the results are only really true if the entire amount of urine in 24 hours is fully and properly collected.
• Urine Protein/Creatinine Ratio (UPCR-Urine Protein Creatinine Ratio), Albumin/Urine Albumatinin Ratio ratio: Randomly taken urine samples (taken at any time of the day). This test replaces the protein dosing test, 24-hour urine albumin, which is convenient for taking samples of test urine and is not affected by the amount of water introduced into the body or the use of weeds.

Urine samples for semi-protein dosing tests (In urine total analysis tests) and Protein/Creatinine ratio (UPCR), Albumin/Creatinine ratio (UACR)uria: Randomized urine sampling, or 2nd urine of the morning. When taking urine samples should be noted: Protein tests in the urine may be falsely positive if in the urine there is blood not from the urinary tract (e.g., Menstruation), semen or secretion from the genital tract; the result is altered if the urine is diluted (e.g., drinking plenty of water, infusion). It is advis recommended to rinse the genitals before taking urine, remove some urine at the beginning of the paddock and then get urine for testing.

Urine 24 hours to quanst quane proteins, albumin: The most important thing is to collect all urine within 24 hours, store cool, do not use preserv preservables. How to collect as follows:

• Prepare:
  • Urine containers: Dry clean, with a tight lid, capacity of about 3 liters (plastic cans should be used).
  • Storage tools: Refrigerator cooler, or storage bin, the best storage temperature is 2-8 degrees Celsius.
  • Urine tools: Dry, clean, mouth wide enough to get urine.
  • Tools for measuring urine (as accurate as possible).
• Urine Collection:
  • Urinate all, then time to start collecting urine
  • From this moment any urination (including urination during a foreing or bathing) must be taken for urine and poured into the can
  • Keep urine containers at cool temperatures (best of 2-8 degrees Celsius)
  • The next day, at the full 24 hours, the last urine poured into the can
  • Mix urine well in the can (by shaking inverted, gently avoid foaming)
  • Measure and record the volume of water (in ml) to notify the laboratory
  • Take 10 ml of well-mixed urine to send the test.

Urine samples can be taken at home, containers need to dry clean, especially no detergents. Urine samples after sampling should be sent to the testing facility in about 1-2 hours, at best less than 1 hour (60 minutes).

Currently, Share99 International Hospital is implementing a Urology – Gravel Screening package to help detect urinary tract diseases early, thereby helping patients reduce treatment time, save costs, increase recovery.

Customers in need can go directly to Share99 Health System nationwide for doctors to consult, examine, treat diseases or make appointments online HERE.

SEE MORE:

• What is proteinuria, what does it mean in the diagnosis of urinary kidney disease?
• What is full protein dosing for?
• Total protein test in blood, urine