What is Creatinine Dosing?

Creatinine dosing is an important basis for the doctor to be able to accurately assess the renal function of the patient. Creatinine will be evaluated through a blood or urine test.

1. The role of Creatinine

Creatinine is the product of Creatin wear and tear on the muscles of the body. Everyone has Creatinine in their blood. End enderthranine creatinine is mainly from the liver, kidneys and pancreas, synthesized from Arginin and Methionin. Out-of-life creatin provided by food. The kidneys maintain Creatinine in the blood at a normal range. Creatinine is eliminated through the kidneys so the concentration of Creatinine accurately reflects the filtration function of the kidneys.

Therefore, normal blood creatinine levels are not changed if the excreted function of the kidneys works normally. In addition to dehydration, only disorders in the kidneys such as acute renal tubular necrosis, angulous inflammation, achitis, obstruction of the urine,… causes Creatinine to increase abnormally. Increased creatinine levels show impaired renal function or kidney disease.

Besides, after meals, Creatinine will usually increase slightly, especially after eating large amounts of protein. In addition, there are some variations during the day in terms of Creatinine: Lowest at 7 a.m. and highest at 7 p.m.

Signs of renal failure in diabetics

The concentration of Creatinine accurately reflects the filtration function of the kidneys

2. When to perform a Creatinine dosing test?

When the kidneys are weakened for any reason, the level of Creatinine in the patient's blood will increase due to the poor ability of the kidneys to discharge Creatinine. Therefore, blood creatinine dosing tests are often carried out to diagnose and evaluate renal function.

A more accurate way of evaluatiing renal function is to calculate how much Creatinine is eliminated from the body by the kidneys. This is called the clearance of Creatinine and it helps the doctor to assess the rate of filtration of the kidneys.

Creatinine tests can be done on a regular basis as part of basic bio-tests. This medical technique can also be indented when the person has an urgent condition or when the doctor suspects that the kidneys are not working well. Some warning signs of impaired renal function include:

  • Fatigue, lack of concentration, insomnia, loss of appetite;
  • Swelling, edema in the area of the face, abdomen, thighs, ankles;
  • Urine is foamy, bloody or coffee-colored;
  • Reduce the amount of urine;
  • Burning sensation when urinating, having abnormal discharge during urination, there is a change in the habit of urination, night urination;
  • Pain in the hip area of the back, under the ribs, near the location of the kidneys;
  • Hypertension.

In addition, the frequency of blood creatinine dosing tests depends on the pathology and risk of kidney damage of each patient. Specifically:

  • Diabetics should perform Creatinine dosing tests at least once a year;
  • People with kidney disease should measure their Creatinine levels regularly to monitor their health status;
  • People with the disease can affect kidney function such as hypertension, diabetes, taking medications that have side effects on the kidneys,… it is also recommended to perform a Creatinine dosing test.

diabetes

Diabetics should perform a Creatinine dosing test at least once a year

3. Creatinine Dosing Tests

3.1 Blood creatinine tests

Creatinine dosing tests in the blood are carried out on a regular basis as part of basic bio chemical tests. In addition, when the patient has an urgent condition or the doctor has doubts about renal function, a blood creatinine test is also in order.

Some of the factors influential in blood creatinine test results include:

  • Some drugs cause creatinine levels in the blood to increase such as high blood pressure drugs, heavy metal chemotherapy drugs, cimetidine, aminoglycosides or other renal-toxic drugs such as cephalosporins;
  • Muscle injury increases Creatinine in the blood;
  • Pregnancy causes lower levels of Creatinine.

3.2 Urine creatinine testing

When renal function is problematic, Creatinine levels accumulate in the body. The Creatinine test in the urine helps to assess whether the kidneys work well or not. Trials measuring 24-hour urine creatinine levels are generally in place for patients with suspected kidney disease. If Creatinine in the body is high can be a warning sign of kidney disease.

4. What is the normal concentration of Creatinine?

Creatinine levels in both urine and blood will be determined and compared. Blood creatinine dosing in healthy females is 0.5-1.1 mg/dl or 44-97 umol/l (SI units) and in healthy men it is 0.6-1.2 mg/dl or 53-106 umol/l (SI unit). In addition, the Creatinine index depends on factors such as age, gender, body weight,… Specifically, elderly people who decrease muscle mass can reduce Creatinine levels. Adolescents have creatinine concentrations of 0.5-1.0 mg/dl, children are 0.3-0.7 mg/dl, young children are 0.2-0.4 mg/dl, and infants are 0.3-1.2 mg/dl.

5. Abnormal results after Creatinine dosing test

  • Increased Creatinine levels: Warning of risk of cochleulitis, aphrhritis, acute renal necrosis, acute and chronic renal failure, decreased blood flow to the kidneys (shock, dehydration, atherosclerosis, congestive heart failure), renal artery stenosis, urinary tract obstruction, renal encephalitis, systophysis , swelling of the kidneys, hypothyroidism, Goutte, head and genus enlarged, enormous, diuretic or anti-blood pressure medication, hypertension, diabetes, renal degeneration, systemic lupus erythematosis, IgA deposition in gloxral glox, kidney stones, multiple bone marrow tumors, renal toxicity, increased blood uric acid, prostate cancer, bladder tumor , uterine tumors, post-peritoneal fibrosis,…
  • Decreased Creatinine levels: Debilitating body, chronic liver disease, decreased muscle mass (muscle failure, muscular dysdyscreas, old age) or pregnancy, fasting, taking anti-kinh drugs,…

Creatinine dosing tests play an important role in the diagnosis, early detection and active treatment of kidney diseases. Therefore, if there is a high risk of kidney disease or warning signs of kidney failure, patients should soon look to reputable medical facilities to perform creatinine concentration tests and other diagnostic methods.

Share99 International Health Hub is one of the hospitals that not only ensures professional quality with a team of leading doctors, modern technology equipment system but also stands out for comprehensive and professional medical examination, consultation and treatment services; civilized, polite, safe and sterilized medical examination and treatment space. Customers who choose to perform tests here can be assured of the accuracy of the test results.

Customers can directly go to Share99 Health System nationwide for examination or contact the hotline here for assistance.

SEE MORE:

  • What is blood protein? What is the normal index?
  • Implications of tests that evaluate renal function
  • Tests to be done to assess renal function
SEE MORE:

  • How to calculate the creatinine clearance system
  • The role of creatinine dosing in the blood
  • Complications of acute – chronic achitis

About: John Smith

b1ffdb54307529964874ff53a5c5de33?s=90&r=gI am the author of Share99.net. I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.

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