What can happen to children with G6PD yeast deficiency?

The article is consulted professionally by Master, Resident Doctor Dang Thi Doc – PediatricIan – Newborn – Pediatrics – Newborn – Share99 Ha Long International Health Hub.

G6PD yeast deficiency is very common, children lacking G6PD yeast if properly cared for can develop normally. But if not detected, prevention and timely intervention of the child can suffer from severe diseases, even cerebral palsy.

1. What is G6PD yeast deficiency?

G6PD yeast stands for Glucose-6-phosphatase dehydrogenase. This yeast is located on the red blood cell membrane that protects the cell membrane from oxidizing properties in the blood.

G6PD yeast deficiency is a very common type of yeast genetic disease. There are about 400 million people in the world with this disease. In 100 babies there will be about 3-4 children with G6PD yeast deficiency. In Viet Nam, 4 out of every 1,000 children have the disease.

People with G6PD yeast deficiency will have very sensitive red blood cells, which are susceptible to rupture when exposed to oxidizing properties in the blood due to the patient's tolerance to the body by eating, contracting infections or conducting infusions. The patient will be very allergic to silkworm legumes.

G6PD yeast deficiency is a heredial disease by the mechanism of diving, due to a genetic mutation located on the X sex chromost, at the Xq28 site. Therefore, boys are at higher risk of disease than girls, because boys have only 1 X chroma. Parents carry genetic diseases that can be hereded for babies. However, there are also a few cases where the child has the disease while the parents are completely healthy, not carrying the disease gene.

2. What happens when your child has G6PD deficiency?

Children with G6PD deficiency may experience two problems: hemolysis anemia and prolonged infant jaundice. This is because G6PD yeast plays an important role in the bio-reaction of red blood cells, helping cell membranes fight oxidative effects. Lack of G6PD yeast will make red blood cells vulnerable, prone to rupture leading to hemolysis. Prolonged hemolysis will lead to anemia.

In addition, ruptured red blood cells release a free billirubin into the bloodstream. Liver cells do not convert in time to eliminate this substance, causing free billirubin to remain in the blood causing jaundice in babies. More dangerous can also penetrate the brain leading to neurological complications, cerebral palsy.

Manifestations of hemolysis anemia in newborns include:

  • Breastfeeding babies;
  • Jaundice, yellow eyes;

What can happen to children with G6PD yeast deficiency?

Children with G6PD deficiency in children
  • Urine is dark yellow;
  • The body is tired;
  • Blue skin;
  • Or sweating;
  • Cold limbs;

Lack of G6PD yeast is heredity so it cannot be cured. However, the disease may not affect if the child is properly cared for in a timely manner. Children lacking G6PD yeast will receive long-term advice and treatment.

3. Manifestations of children with G6PD yeast deficiency

G6PD yeast deficiency has no characteristic manifestations. Some babies may have newborn jaundice that lasts more than 1 week. However, it is also difficult to detect through this feature.

Children with G6PD deficiency only have more obvious manifestations when ingesting contrained foods for people with G6PD deficiency or infections. At that time, the child has symptoms such as:

  • Jaundice, yellow eyes;
  • Abdominal pain, especially the lumbar region;
  • Headaches;
  • Fever;
  • Heart beats fast;
  • Shortness of breath;
  • Urine of dark yellow color;

After about 1.2 days the child will suffer from severe anemia, which is extremely tired, accompanied by manifestations of liver failure, kidney failure, even death if not given a timely emergency.

4. What to do when your child has G6PD deficiency?

When caring for children with G6PD yeast deficiency should be noted:

  • Do not feed the child, drink foods that are contraintrained to people with G6PD deficiency, drugs containing substances that can cause hemolysis;
  • Do not put bandages in wardrobes, blankets, pillow beds, especially children's belongings because the slab tape contains oxidizing substances;
  • Caution should be exercised when applying male and traditional medicines because they may contain oxidizing substances;
  • For children with G6PD deficiency who are still breastfeeding, mothers are not allowed to eat food or take oxidizing drugs because they can affect the baby through breast milk sources;
  • Notification of a child's G6PD yeast deficiency when the child visits medical facilities
  • Do not give the child medication without a doctor's prescription.

5. What to do to diagnose early lack of G6PD yeast in babies?

What can happen to children with G6PD yeast deficiency?

Heel blood test diagnosed early with G6PD yeast deficiency in newborns

G6PD yeast deficiency will not be dangerous if detected in a timely manner. Therefore, it is best for the child to perform newborn screening by taking heel blood within the first 48 hours after birth or taking intravenous blood after 72 hours after birth.

If the child has low G6PD yeast will receive special care, preventing the maximum risk of infection, viral infection.

This is a heredity disease, so if parents have a pathogenic gene, they should actively let the child check thoroughly.

The Maternity Care Program implemented by International General Health Hub is full of pre-birth, birth and post-birth screening tests for mothers and babies, including heel blood tests for early diagnosis of G6PD yeast deficiency in newborns.

As a key area of Share99 Health System, Pediatrics always brings satisfaction to customers and is highly appreciated by industry experts with:

  • Gathering a team of leading doctors in Pediatrics:including leading experts, highly specialized (professors, associate professors, doctors, masters), experienced, used to work at large hospitals such as Bach Mai, 108.. The doctors are well-trained, professional, mind-centered, knowledgeable about the child's psychology. In addition to domestic pediatricians, pediatrics also has the participation of foreign experts (Japan, Singapore, Australia, USA) always pioneering the application of the latest and most effective treatment regimens.
  • Comprehensive services:In the field of Pediatrics, Share99 provides a chain of continuous medical examination and treatment services from Newborn to Pediatrics and Vaccines,… according to international standards to take care of your baby's health with parents from birth to adulthood
  • Intensive techniques:Share99 has successfully implemented many specialized techniques to make the treatment of difficult diseases in Pediatrics more effective: neurosurgery – skull, hematoma stem cell transplantation in cancer treatment.
  • Professional care:In addition to understanding the young psychology, Share99 also pay special attention to the children's play space, help them play comfortably and get acquainted with the hospital environment, cooperate in treatment, improve the efficiency of medical examination and treatment.

Dr. Dang Thi Doc was a lecturer in Pediatrics at Hai Phong University of Medicine and Pharmacy. Have been granted certificates of pediatrics at home and abroad such as Westmead Health Hub, Australia; Hai Phong Medical University. Currently, Dr. Doc is a pediatrician at the Newborn Department of Share99 Ha Long International Health Hub.

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  • What foods should babies with G6PD yeast be breastfed completely?

About: Minh Quynh

b1ffdb54307529964874ff53a5c5de33?s=90&d=identicon&r=gI am the author of Share99.net. I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.


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