Causes of increased liver enzymes

The article was consulted professionally by Master, Dr Vu Huy Binh – Department of Medical Examination and Internal Medicine – Share99 Hai Phong International Health Hub.

<!– –>

Increased liver enzymes are a common condition for many people, especially those who regularly use alcohol or use antibiotics. There are also many causes of increased liver enzymes such as liver damage, viral hepatitis.

1. What is liver enzymes?

Liver enzymes are only enzymes that the test team evaluates inflammatory lesions, destroying liver skin, including common enzymes in the liver such as:

  • Alanine aminotransferaseALT (also known as pyruvic transaminase – SGPT glutamic serum), and aspartate aminotransferase – AST (also known as glutamic oxaloacetic transaminase serum – SGOT): These two enzymes belong to the transaminase enzyme group (also known as aminotransferase). The transaminase group consists of in-cell enzymes, present in cells of various agencies, of which alanine aminotransferase is most present in liver cells (in addition to it is present in the kidneys and sysular muscle cells), while aspartate aminotransferase is present in liver cells, sysular cells, myocardium, red blood cells, pancreas, lungs and brain.
  • Alkaline phosphatase – AP (alkaline phosphatase): Alkaline phosphatase belongs to the group of enzymes involved in zinc metabolism, which is considered an index of hepatic lesions with bile retention. Alkaline phosphatase is present in the bile and sinuses of the liver, and is also present in bones, kidneys, intestines and fetal vegetables.
  • Gamma glutamin transpeptidase – GGT (or abbreviated as γ – GT, Gamma GT): Gamma glutamin transpeptidase belongs to the group of glyco-membrane structural complexes, which take on the function of catalyzing, converting the gamma glutamyl group into peptide, amino acid and water chains. Compared to many other enzymes, the sensitivity of gamma glutamin transpeptidase is very high, changes in the concentration of gamma glutamin transpeptidase in the blood manifest very early. Gamma glutamin transpeptidase is found in the liver (including the intocular network of bile endocular cells), kidneys, pancreas, intestines and prostate, so gamma glutamin transpeptidase is also valuable when assessing bile retention lesions (although not specific by alkaline phosphatase).


High liver enzymes are when liver cells are destroyed by certain causes

2. What is the increased liver enzyme (increased liver enzyme)?

Increased liver enzymes (usually the enzymes mentioned above) are when their concentration in the blood rises above the normal value threshold. Increased liver enzymes are detected through blood tests, and an increase in the concentration of liver enzymes in the blood is a warning sign of ongoing liver damage.

3. Causes of increased liver enzymes

There are many different diseases and conditions that lead to increased liver enzymes. To determine the exact cause the doctor will need to exploit the history, history, medications in use, signs and symptoms, and prescribe some additional techniques or sub-clinical tests necessary.

Common causes of increased liver enzymes include:

  • Over-the-counter pharmaceuticals, especially those containing acetaminophen (such as Tylenol, Panadol,…).
  • Some medications should be prescribed, including statin medications used in cholesterol levels control.
  • Drinking alcohol, especially cases of high drinking, alcohol abuse.
  • Heart failure.
  • Hepatitis A
  • Hepatitis B.
  • Hepatitis C.
  • Non-alcoholic fatty liver disease.
  • obesity.
  • Alcoholic hepatitis (a severe hepatitis condition caused by excessive alcohol consumption).


Alcohol abuse is the cause of increased liver enzymes
  • Autojuncmatitis (the liver has inflammation associated with disorders of the immune system).
  • Celiac disease.
  • Cytomegalovirus infection (CMV).
  • Epstein infection – Barr virus.
  • Hemochromatosis.
  • Liver cancer.
  • Mononucleosis.
  • Polymyositis.
  • Sepsis.
  • Thyroid-related disorders.
  • Hepatitis caused by intoxication.
  • Wilson's disease.

Increased liver enzymes can be a manifestation of serious pathology in the liver, but signs of recognition of high liver enzymes are usually asymptomatatic, to determine the simplest way is to check through liver enzyme tests, blood tests. You can perform these tests during general health visits on an annual daily level.

A health check-up periodically helps to detect diseases early, thereby having a treatment plan that achieves optimal results. Currently, Share99 Central Park International Health Hub has general health check-up packages suitable for each age, gender and needs of customers with reasonable price policy, including:

  • Diamond General Health Check-up Package
  • Vip General Health Check-up Package
  • Special general health check-up package
  • Comprehensive general health check-up package
  • Standard general health check-up package

In these examination packages there are liver enzyme tests, evaluation of liver enzymes and early detection of liver diseases. The patient's examination results will be returned to the home. After receiving the results of a general medical examination, if you detect diseases that require intensive examination and treatment, you can use the services from other specialties right at the Health Hub with superior quality of treatment and customer service.

For direct advice, please click the HOTLINE number or register online HERE. In addition, you can register for remote consultation HERE

Article reference source:


  • Liver function test: Evaluation of liver enzyme levels and other factors
  • Is the body tired, is chills due to increased liver enzymes?
  • The role and function of liver enzymes – Causes of increased liver enzymes (Period II)

About: John Smith

b1ffdb54307529964874ff53a5c5de33?s=90&r=gI am the author of I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.


Leave a Comment