Treatment orientations for cancer of the lining of the uterus

The article was consulted professionally by Master, Dr Trinh Thi Thanh Huyen – Obstetrics and Gynecology Department – Share99 Hai Phong International Health Hub.

Cancer of the lining of the uterus is a cancer that comes from the lining of the uterus. The disease is treatable and the success rate after surgery is much higher than other cancers.

1. What is cancer of the lining of the uterus?

Endometrial cancer is malignant melanoma that is originally from the endometrial tissue, which often distinguishes the form of glands, it is capable of penetrating the muscle layer and spreading to distant places. Cancer of the lining of the uterus ranks 6th among cancers in women and 2nd in gynecologic cancer.

2. Risk factors for cancer of the lining of the uterus

  • Endo noising factors: Prolonged estrogen intensity, ovary release disorders, polycystic ovarysyndrome , early puberty, late menopause.
  • Genetic factors: Families with endometrial cancer, breast cancer, colon cancer (Lynch syndrome)
  • Fitness: obesity, high bloodpressure, diabetes mellitus
  • Diet high in animal fat
  • Use Tamoxifen.

insulin resistance manifestations of obesity

Obesity is one of the causes of cancer of the lining of the uterus

3. Diagnosis of cancer of the lining of the uterus

3.1 Clinical diagnosis

  • Abnormal vaginal bleeding: in premenmenausal women, while menstruation shows signs of menstrualdisorders, menstruation,haemorrhagic, meningausal women have abnormal vaginal hemorrhages, this symptom is very common, accounting for 80% of cases.
  • Vaginal discharge: discharge is usually caused by bacterial infections, blood and necrolyses that cause odors, which is present in about 30% of patients
  • The disease progresses at a late stage: the patient presentes with pain caused by invasiveness, compression, hematoma, abdominal grip,..
  • Physical symptoms when the doctor examines the vagina manually and the duck bill: at an early stage the uterus usually has little change in size and density. Late stages of the uterus are invasive, sticky, less mobile, invasive arc, vagina, rectum,…

3.2 Sub-clinical tests

  • Ultrasound: Ultrasound of the vaginal fall helps to assess the thickness and structure of the lining of the uterus, the degree of invasiveness into the muscles of the uterus, the exclusion of other pelvic diseases; general abdominal ultrasound to record the spread and spread of the disease.
  • Endometrial biosy: this is a mandatory requirement in the diagnosis of endometrial cancer, in order to assess the lesion as benign or malignant and histic, histic motifs, endometrial or cervical primary cancer.
  • Endoscopy of the uterus: this test allows to see the lesion and determine the degree of surface spread and orientation for the bioscopy at the right site of the lesion
  • Comoclassography (CT scan), abdominal resonance imaging (MRI) and PET CT: helps to assess the degree of invasiveness, the spread of the tumor, the metalysed lymphadenopathy.
  • Other tests: lung x-ray detects lung microscopic,CA125 bio-indicators increase in the range of 50-60% of cases of the disease, beta hCG to exclude pregnancy in the uterus, bone radiation if bone microscopic, UIV scan, bladder, rectal scan if invasive tumors of these agencies are suspected.

4. Classification of disease phase according to FIGO 2009

  • Stage I: tumors in the body of the uterus
    • IA: in endometrial or invasive tumors <1⁄2 bề dày cơ tử cung
    • IB: invasive tumors >=1⁄2 of the thickness of the muscles of the uterus.
  • Phase II: Hump spreads to cervical padment tissue
  • Stage III: local or regional spread of humps
    • IIIA: veseal invasive humps or appjunctiva
    • IIIB: vaginal and/or uterus invasive tumors
    • IIIC: metalysed pelvic lymph node or abdominal aortic edge ganglia
  • Stage IV: invading the pelvic area or having distant migrations
    • IVA: tumor that invades the bladder or rectum
    • IVB: disjunctivitis (inguinal lymph nodes, lungs, liver, bones, abdominal peritoneum,…)

5. Methods of treatment of cancer of the lining of the uterus

Treatments for cancer of the lining of the uterus include:

  • Surgical treatment: Surgery is a top priority in the treatment of cancer of the lining of the uterus. There are two surgical methods: abdominal open surgery and laparoscopic surgery. Depending on the case, a full uterus is in order to be removed, two appjunctiva, or a wide-range uterusection with a lymph node, a large conjunction should be cut off through the abdomen to clearly observe the coordinated lesions.
  • Radiotherapy: This is the second most effective treatment in the treatment of cancer of the lining of the uterus. Radiotherapy in dinhed for late-stage cancer or post-surgery supportive treatment
  • End end of end of life in case of late stages.
  • Chemotherapy: Less effective, only when relapsed in young women.

The selection and coordination of treatments depends on the specific stage of the disease of each patient

  • Stage 1: The doctor prescribes a complete removal of the uterus, a lateral appendix and removal of the pelvic lymph node, the aortic edge lymph node. Accordingly, complementary radiation treatment when there are bad preexressing factors (hism hism hismieses 2 or 3, or invasively above 1⁄2 of the muscle layer depth). If in case the cancer of the lining of the uterus has spread down the cervical tube and infiltrated, Wertheim surgery must be applied.
  • Stage 2: Complete uterus removal, two sub-parts and ganglion. After 4-6 weeks of radiation. If the lesion in the cervical is large, the radiation will be before, after 4-6 weeks, the surgery will be carried out.
  • Stage 3: Surgery and radiotherapy remain the main treatments. If surgery is possible, a complete uterus and radiotherapy, otherwise radiotherapy with a localized radium needle and hormonal chemotherapy.
  • Stage 4: The person with the disease is at a late stage or relapses in distant locations, can treat anti-pain radiation, fight bleeding and compression. Combination of end end end of end end of life.

After treatment, patients should be monitored every 3 months for the first 2 years, every 6 months for the next 2 years and then once a year.

Middle-aged women

Women over the age of 40 are more susceptible to the disease, so they need to be tested for gynecology cells to prevent the disease

For the prevention of the disease, women >40 years old if the gynecologic cell test has endometrial glands that need to be sucked in the uterus to perform hism hisbular tests, meningausal women with abnormal signs of blood need to go for an ultrasound to assess the endorateal thickness, endoscopy and obtain the product for hism hisbular testing , especially those who are obese or have a history of Tamoxifen treatment. Early examination and detection of the disease increases the effectiveness of treatment and survival of the patient.

Endometrial cancer is a common disease in women beyond the age of 50, which can be treated if detected and treated at an early stage. Therefore, women >40 years old should have regular gynecologic health examinations to detect gynecologic diseases in the pre-menices.

Master. Dr. Trinh Thi Thanh Huyen is highly trained in obstetric ultrasound, laparoscopic surgery and endoscopy at the National Health Hub of Obstetrics and Gynecology and has more than 13 years of experience working at Hai Phong Obstetrics and Gynecology Health Hub.

Currently, the doctor is a doctor of obstetrics and gynecology at Share99 Hai Phong International Health Hub

For direct advice, please click hotline number or register online HERE. In addition, you can register for remote consultation HERE

SEE MORE:

  • Endometrial Cancer: Symptoms, Causes and Screening
  • Imaging in endometrial cancer assessment
  • 11 questions – full answers about polycystic ovaries

About: John Smith

b1ffdb54307529964874ff53a5c5de33?s=90&r=gI am the author of Share99.net. I had been working in Vinmec International General Hospital for over 10 years. I dedicate my passion on every post in this site.

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