hCG is a hormone secreted in the early stages of pregnancy, which plays an important role in the nourishment and protection of pregnancy. Monitoring hCG levels can help assess pregnancy health status. What is high hCG and in which cases hCG is the issue of interest to many women.
1. What is hCG hormone?
hCG (short for Human chorinoic Gonadotropin) is a hormone that is essentially glycoprotein, produced by placenta cells in the early stages of pregnancy. Tests can detect hCG hormones in the blood after about 11 days after pregnancy, after 12-14 days it is possible to detect the hormone hCG in the urine.
In the early stages of pregnancy, in the majority of women, hCG levels double every 48 to 72 hours until hCG reaches its highest concentration during pregnancy at about the 8th-10th week. After this period, hCG will gradually decrease until birth.
HCG hormones play an important role in protecting and nourishing pregnancy. HCG hormone levels test helps detect early pregnancy and monitor pregnancy development.
HCG concentrations will vary with gestational age as follows:
- Pregnancy 3 weeks: 5-50 mUI/ml.
- Pregnancy 4 weeks: 5-426 mUI/ml.
- Pregnancy 5 weeks: 18-7,340 mUI/ml.
- Pregnancy 6 weeks: 1,080-56,500 mUI/ml.
- Pregnancy 7-8 weeks: 7,650-229,000 mUI/ml.
- Pregnancy 9-12 weeks: 25,700-288,000 mUI/ml.
- Pregnancy 13-16 weeks: 13,300-254,000 mUI/ml.
- Pregnancy 25-40 weeks: 3,640-117,000 mUI/ml.
After birth from 4-6 weeks, hCG levels will return to normal as before pregnancy is < 5 mUI/ml.
2. What is high hCG?
High hCG is when the test result of hCG levels in the blood is higher than the usual range. To determine the case of high hCG the doctor will prescribe multiple hCG tests 2-3 days apart instead of relying on a single result. Since hCG levels vary greatly among pregnant women, there are women who have an increased hCG concentration but the pregnancy is still completely normal. hCG sometimes increases only due to incorrect gestational age calculation, however, in many cases high hCG is a manifestation of pathology and abnormalities in pregnancy.
3. In what cases does hCG rise?
3.1. Incorrect gestational age calculation
Gestational age is calculated from the first menstrual day of the last menstruation, if it is not clearly remembered or the menstrual cycle is irregular, it is easy to misi calculate the gestational age. HCG test results are high because it is possible that the real gestational age is higher than the gestational age you think.
3.2. Multiple pregnancies
Multiple pregnancies are the phenomenon of multiple pregnancies developing in the mother's uterus. Multi-pregnancy women will have more severe pregnancy symptoms, chest pain and development, faster weight gain, and hCG levels also increase by about 30-50% higher than normal single pregnancy women. However, hCG testing alone is not enough for a multi-pregnancydiagnosis , the doctor must prescribe many tests and other methods of exploration, especially ultrasound.
3.3. Egg pregnancy
Egg pregnancy (or incubation) is a medical condition in which there is an abnormal growth of the layer of cultured cells in the placenta, forming bags filled with water, sticking together like bunches of grapes. Egg-laying is usually a benign form of tumor and is not a real fetus, however there are also many cases where the egg is malignant, causing many dangerous health complications. In egg production, hCG concentrations are usually very high, which can be over 30,000 mUI/ml.
HCG testing is also in place to monitor the response after egg-laying treatment. Patients may be required to have a hCG test periodically for two years from the time of treatment to ensure health has stabilized and no complications have been present.
3.4. Down disease
Down syndrome is a chroma disorder during cell division that leads to an excess of 1 chrom chrom chroma no. 21. The risk factors for down disease are elderly pregnant women or parents carrying modified genes. When the fetus has down disease, the hCG concentration in the mother's blood increases while the amount of AFP blood decreases.
4. What to do when hCG rises?
As hCG levels increase, the doctor will make a clinical examination and prescribe additional tests and exploration methods to determine the specific condition of the patient. The risks that can be encountered when hCG increases are dangerous, which can affect the mother's health and fetal health if not detected, consulted, treated in a timely manner.
Share99 International Health Hub offers a full maternity care program for women from the very beginning of pregnancy from the first months with a full range of pregnancy examinations, 3D ultrasounds, 4D routines and routine tests to ensure the mother is always healthy and the fetus develops comprehensively. Obstetrics and Gynecology will be consulted and checked under the close supervision of experienced and professional obstetrician, helping mothers have more knowledge to protect their health during pregnancy as well as minimize complications affecting mothers and children.
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